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Renova Cream or Retin-A are the best brands of Tretinoin, a potent chemical that is a derivative of Vitamin A, effective in treating wrinkles, mottled coloring, and rough or sun-damaged skin. Generally Renova Generic Tretinoin Cream is used for Acne treatments and certain Skin Disorder. Renova was approved in 1996 by the FDA to treat sun-related problems. Renova Cream is also called Acne Cream. Tretinoin sets off molecules [called retinoid receptors] in the skin cells that cause certain intracellular processes to take place, including synthesis of proteins [such as collagen and elastin], cell growth and differentiation, and production of the fatty lubricant by the sebaceous glands of the skin. Renova cream is available in the form of 20mg and 15mg tubes.